Open medical sources

Research library

Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

Research corpus

4,000+ records

Systematic review / meta-analysis 2023
Mental health

The prevalence of probable mental health disorders among hospital healthcare workers during COVID-19: A systematic review and meta-analysis.

Journal of affective disorders

Objectives The mental health impacts of the COVID-19 pandemic continue to be documented worldwide with systematic reviews playing a pivotal role. Here we present updated findings from our systematic review and meta-analysis on the mental health impacts among h

Systematic review / meta-analysis 2023
Infections and immunity

Hyperinflammatory Response in COVID-19: A Systematic Review.

Viruses

COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory response that cause systemic inflammation are extremely linked to its severity. This resear

Systematic review / meta-analysis 2023
Prevention and public health

Global prevalence of mild cognitive impairment among older adults living in nursing homes: a meta-analysis and systematic review of epidemiological surveys.

Translational psychiatry

Mild cognitive impairment (MCI) is the early stage of cognitive impairment between the expected cognitive decline of normal aging and the more serious decline of dementia. This meta-analysis and systematic review explored the pooled global prevalence of MCI am

Systematic review / meta-analysis 2023
Children's health

Live birth rate after female fertility preservation for cancer or haematopoietic stem cell transplantation: a systematic review and meta-analysis of the three main techniques; embryo, oocyte and ovarian tissue cryopreservation.

Human reproduction (Oxford, England)

Study question What are the chances of achieving a live birth after embryo, oocyte and ovarian tissue cryopreservation (OTC) in female cancer survivors? Summary answer The live birth rates (LBRs) following embryo and oocyte cryopreservation are 41% and 32%, re

Systematic review / meta-analysis 2023
Mental health

The effect of adverse childhood experiences on chronic pain and major depression in adulthood: a systematic review and meta-analysis.

British journal of anaesthesia

Background Adverse childhood experiences have been linked to increased multimorbidity, with physical and mental health consequences throughout life. Chronic pain is often associated with mood disorders, such as major depressive disorder (MDD); both have been l

Systematic review / meta-analysis 2023
General medicine and research

Fragmented care and chronic illness patient outcomes: A systematic review.

Nursing open

Aim This systematic review examined recent studies on fragmented care of patients with chronic illnesses in the United States to examine the association between fragmented care and patient outcomes. Design Systematic review. Methods Studies published from Janu

Systematic review / meta-analysis 2023
Brain and nervous system

Changes in Gut Microbiota and Multiple Sclerosis: A Systematic Review.

International journal of environmental research and public health

Introduction Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease mediated by autoimmune reactions against myelin proteins and gangliosides in the grey and white matter of the brain and spinal cord. It is considered one of the most commo

Systematic review / meta-analysis 2023
Mental health

Barriers and facilitators to physical activity for young adult women: a systematic review and thematic synthesis of qualitative literature.

The international journal of behavioral nutrition and physical activity

Background Physical activity (PA) has many benefits in preventing diseases and maintaining physical and mental health. Women, in particular, can benefit from regular PA. However, women's PA did not increase over the past decade globally, and the situations fac

Systematic review / meta-analysis 2023
Cancer and oncology

The Prevalence of HPV in Oral Cavity Squamous Cell Carcinoma.

Viruses

Human papillomavirus (HPV) is an important risk factor in a subset of head and neck squamous cell carcinomas (HNSCC), but the association with oral cavity squamous cell carcinomas (OCSCC) remains controversial. This study aimed to identify the prevalence of HP

Systematic review / meta-analysis 2023
Cancer and oncology

3D In Vitro Models for Investigating the Role of Stiffness in Cancer Invasion.

ACS biomaterials science & engineering

Background Tumorigenesis is attributed to the interactions of cancer cells with the tumor microenvironment through both biochemical cues and physical stimuli. Increased matrix deposition and realignment of the collagen fibers are detected by cancer cells, indu

Systematic review / meta-analysis 2023
Brain and nervous system

Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Background Intrathecal immunoglobulin-G synthesis is a hallmark of multiple sclerosis (MS), which can be detected by oligoclonal IgG bands (OCB) or by κ-free light chains (κ-FLC) in cerebrospinal fluid. Objective To perform a systematic review and meta-analysi

Systematic review / meta-analysis 2023
Lungs and breathing

Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary disease (COPD).

The Cochrane database of systematic reviews

Background Inspiratory muscle training (IMT) aims to improve respiratory muscle strength and endurance. Clinical trials used various training protocols, devices and respiratory measurements to check the effectiveness of this intervention. The current guideline

Systematic review / meta-analysis 2024
Cancer and oncology

Patient Navigation in Cancer Treatment: A Systematic Review.

Current oncology reports

Purpose of review Patient navigation promotes access to timely treatment of chronic diseases by eliminating barriers to care. Patient navigation programs have been well-established in improving screening rates and diagnostic resolution. This systematic review