Open medical sources

Research library

Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

Research corpus

4,011+ records

Systematic review / meta-analysis 2026
Diabetes and metabolism

Efficacy of Metformin in Prevention of Glucocorticoid-Induced Hyperglycemia in Patients Without Diabetes: A Meta-Analysis.

Endocrinology, diabetes & metabolism

Purpose The glucocorticoids are increasingly being used in the management of different autoimmune conditions and cancers. Our meta-analysis aims to leverage metformin's potential to reverse the metabolic complications of glucocorticoids by activating AMP-activ…

Systematic review / meta-analysis 2026
General medicine and research

Diabetic Foot Ulceration in Dialysis-Dependent End-Stage Kidney Disease: A Systematic Review of Epidemiology, Clinical Outcomes and Mortality Risk.

Diabetes/metabolism research and reviews

Background Diabetic foot ulceration (DFU) and lower limb complications are highly prevalent in people with end-stage kidney disease (ESKD), particularly those receiving dialysis; however, the overall burden and outcomes remain incompletely characterised. This …

Systematic review / meta-analysis 2026
Infections and immunity

Skin Closure Techniques After Cardiac Implantable Electronic Device Implantation and Their Impact on Pocket Complications: A Systematic Review and Meta-Analysis.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

Background Cardiac implantable electronic device (CIED) implantation, including pacemakers, implantable cardioverter-defibrillators, and cardiac resynchronization therapy systems, is increasingly performed worldwide. Despite advances in implantation techniques…

Systematic review / meta-analysis 2026
Brain and nervous system

Impact of Different Types of Sedentary Behaviour on Cognitive Function in Older Adults: A Systematic Review.

Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals

Issue addressed Sedentary behaviour (SB) is a relevant determinant of health in ageing, yet its effects on cognitive function remain inconclusive. The literature often treats SB as a homogeneous exposure, without considering that different sedentary activities…

Systematic review / meta-analysis 2026
Children's health

Diagnostic performance of point-of-care ultrasound for pediatric skull fractures: A systematic review and meta-analysis.

The Journal of international medical research

ObjectivePediatric head trauma is common, but computed tomography exposes children to ionizing radiation. This systematic review and meta-analysis evaluated the diagnostic accuracy of point-of-care ultrasound for pediatric skull fractures and clarified its rol…

Clinical guideline 2024
Children's health

Revised ISHAM-ABPA working group clinical practice guidelines for diagnosing, classifying and treating allergic bronchopulmonary aspergillosis/mycoses.

The European respiratory journal

Background The International Society for Human and Animal Mycology (ISHAM) working group proposed recommendations for managing allergic bronchopulmonary aspergillosis (ABPA) a decade ago. There is a need to update these recommendations due to advances in diagn…

Clinical guideline 2018
Women's health

International guidelines for groin hernia management.

Hernia : the journal of hernias and abdominal wall surgery

Introduction Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize comp…

Clinical guideline 2023
Heart and blood vessels

A brain-based definition of death and criteria for its determination after arrest of circulation or neurologic function in Canada: a 2023 clinical practice guideline.

Canadian journal of anaesthesia = Journal canadien d'anesthesie

This 2023 Clinical Practice Guideline provides the biomedical definition of death based on permanent cessation of brain function that applies to all persons, as well as recommendations for death determination by circulatory criteria for potential organ donors …

Clinical guideline 2024
Children's health

ISPAD Clinical Practice Consensus Guidelines 2024: Screening, Staging, and Strategies to Preserve Beta-Cell Function in Children and Adolescents with Type 1 Diabetes.

Hormone research in paediatrics

The International Society for Pediatric and Adolescent Diabetes (ISPAD) guidelines represent a rich repository that serves as the only comprehensive set of clinical recommendations for children, adolescents, and young adults living with diabetes worldwide. Thi…

Clinical guideline 2024
Heart and blood vessels

Cardioneuroablation for the treatment of reflex syncope and functional bradyarrhythmias: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS) and the Latin American Heart Rhythm Society (LAHRS).

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Cardioneuroablation has emerged as a potential alternative to cardiac pacing in selected cases with vasovagal reflex syncope, extrinsic vagally induced sinus bradycardia-arrest or atrioventricular block. The technique was first introduced decades ago, and its …

Clinical guideline 2025
Digestive system

European guidelines for the diagnosis and treatment of pancreatic exocrine insufficiency: UEG, EPC, EDS, ESPEN, ESPGHAN, ESDO, and ESPCG evidence-based recommendations.

United European gastroenterology journal

Pancreatic exocrine insufficiency (PEI) is defined as a reduction in pancreatic exocrine secretion below the level that allows the normal digestion of nutrients. Pancreatic disease and surgery are the main causes of PEI. However, other conditions and upper gas…

Clinical guideline 2024
Cancer and oncology

Joint EANM/EANO/RANO/SNMMI practice guideline/procedure standards for diagnostics and therapy (theranostics) of meningiomas using radiolabeled somatostatin receptor ligands: version 1.0.

European journal of nuclear medicine and molecular imaging

Purpose To provide practice guideline/procedure standards for diagnostics and therapy (theranostics) of meningiomas using radiolabeled somatostatin receptor (SSTR) ligands. Methods This joint practice guideline/procedure standard was collaboratively developed …

Clinical guideline 2024
Children's health

International Society for Pediatric and Adolescent Diabetes Clinical Practice Consensus Guidelines 2024: Diabetes Technologies - Insulin Delivery.

Hormone research in paediatrics

The International Society for Pediatric and Adolescent Diabetes (ISPAD) guidelines represent a rich repository that serves as the only comprehensive set of clinical recommendations for children, adolescents, and young adults living with diabetes worldwide. Thi…

Clinical guideline 2019
General medicine and research

Update of Guidelines for laparoscopic treatment of ventral and incisional abdominal wall hernias (International Endohernia Society (IEHS))-Part A.

Surgical endoscopy

In 2014, the International Endohernia Society (IEHS) published the first international "Guidelines for laparoscopic treatment of ventral and incisional abdominal wall hernias." Guidelines reflect the currently best available evidence in diagnostics and therapy…

Clinical guideline 2021
Cancer and oncology

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender.

The British journal of surgery

Background Lynch syndrome is the most common genetic predisposition for hereditary cancer but remains underdiagnosed. Large prospective observational studies have recently increased understanding of the effectiveness of colonoscopic surveillance and the hetero…