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Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

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Systematic review / meta-analysis 2021
Bones, joints and rehabilitation

Neuromuscular Function of the Knee Joint Following Knee Injuries: Does It Ever Get Back to Normal? A Systematic Review with Meta-Analyses.

Sports medicine (Auckland, N.Z.)

Background Neuromuscular deficits are common following knee injuries and may contribute to early-onset post-traumatic osteoarthritis, likely mediated through quadriceps dysfunction. Objective To identify how peri-articular neuromuscular function changes over t

Systematic review / meta-analysis 2019
Infections and immunity

The role of mesenchymal stem cells in hematopoietic stem cell transplantation: prevention and treatment of graft-versus-host disease.

Stem cell research & therapy

Background The use and effectiveness of hematopoietic stem cell transplantation (HSCT) are limited by lethal complications, i.e., acute and chronic graft-versus-host disease (aGVHD and cGVHD, respectively), in which immune cells from the donor attack healthy r

Systematic review / meta-analysis 2018
Diabetes and metabolism

Intermittent versus continuous energy restriction on weight loss and cardiometabolic outcomes: a systematic review and meta-analysis of randomized controlled trials.

Journal of translational medicine

Background This systematic review and meta-analysis summarized the most recent evidence on the efficacy of intermittent energy restriction (IER) versus continuous energy restriction on weight-loss, body composition, blood pressure and other cardiometabolic ris

Systematic review / meta-analysis 2018
General medicine and research

Propofol vs. inhalational agents to maintain general anaesthesia in ambulatory and in-patient surgery: a systematic review and meta-analysis.

BMC anesthesiology

Background It is unclear if anaesthesia maintenance with propofol is advantageous or beneficial over inhalational agents. This study is intended to compare the effects of propofol vs. inhalational agents in maintaining general anaesthesia on patient-relevant o

Systematic review / meta-analysis 2022
Mental health

Sleep Quality and Aging: A Systematic Review on Healthy Older People, Mild Cognitive Impairment and Alzheimer's Disease.

International journal of environmental research and public health

Aging is characterized by changes in the structure and quality of sleep. When the alterations in sleep become substantial, they can generate or accelerate cognitive decline, even in the absence of overt pathology. In fact, impaired sleep represents one of the

Systematic review / meta-analysis 2018
Mental health

The power of support from companion animals for people living with mental health problems: a systematic review and narrative synthesis of the evidence.

BMC psychiatry

Background There is increasing recognition of the therapeutic function pets can play in relation to mental health. However, there has been no systematic review of the evidence related to the comprehensive role of companion animals and how pets might contribute

Systematic review / meta-analysis 2019
Cancer and oncology

Pretreatment lactate dehydrogenase may predict outcome of advanced non small-cell lung cancer patients treated with immune checkpoint inhibitors: A meta-analysis.

Cancer medicine

The main aim of this study is to investigate whether baseline lactate dehydrogenase (LDH) is associated with the clinical outcome of non small-cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICIs). We searched Pubmed, the Cochrane

Systematic review / meta-analysis 2020
Prevention and public health

A systematic review of intimate partner violence interventions focused on improving social support and/ mental health outcomes of survivors.

PloS one

Background Intimate partner violence (IPV) is a key public health issue, with a myriad of physical, sexual and emotional consequences for the survivors of violence. Social support has been found to be an important factor in mitigating and moderating the conseq

Systematic review / meta-analysis 2018
Prevention and public health

Evidence of synergistic relationships between HIV and Human Papillomavirus (HPV): systematic reviews and meta-analyses of longitudinal studies of HPV acquisition and clearance by HIV status, and of HIV acquisition by HPV status.

Journal of the International AIDS Society

Introduction Observational studies suggest HIV and human papillomavirus (HPV) infections may have multiple interactions. We reviewed the strength of the evidence for the influence of HIV on HPV acquisition and clearance, and the influence of HPV on HIV acquisi

Systematic review / meta-analysis 2020
Prevention and public health

Evidence of the Importance of Dietary Habits Regarding Depressive Symptoms and Depression.

International journal of environmental research and public health

Background Mental illness is one of the fastest rising threats to public health, of which depression and anxiety disorders are increasing the most. Research shows that diet is associated with depressive symptoms or depression (depression). Aim This study aimed

Systematic review / meta-analysis 2019
Cancer and oncology

Risk of Pneumonitis and Pneumonia Associated With Immune Checkpoint Inhibitors for Solid Tumors: A Systematic Review and Meta-Analysis.

Frontiers in immunology

Background: We performed a systematic review and meta-analysis to evaluate the risk of pneumonitis and pneumonia associated with immune checkpoint inhibitors (ICIs) for solid tumors. Methods: The following keywords were used in searching the Embase and PubMed

Systematic review / meta-analysis 2019
Diabetes and metabolism

A systematic review and meta-analysis estimating the population prevalence of comorbidities in children and adolescents aged 5 to 18 years.

Obesity reviews : an official journal of the International Association for the Study of Obesity

Evidence for the health impact of obesity has largely focussed on adults. We estimated the population prevalence and prevalence ratio of obesity-associated comorbidities in children and adolescents aged 5 to 18 years. Five databases were searched from inceptio