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Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

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Systematic review / meta-analysis 2024
Brain and nervous system

Efficacy of the iron-chelating agent, deferiprone, in patients with Parkinson's disease: A systematic review and meta-analysis.

CNS neuroscience & therapeutics

Introduction Several studies have reported iron accumulation in the basal ganglia to be associated with the development of Parkinson's Disease (PD). Recently, a few trials have examined the efficacy of using the iron-chelating agent Deferiprone (DFP) for patie

Systematic review / meta-analysis 2024
General medicine and research

How far can we go? A 20-year meta-analysis of dental implant survival rates.

Clinical oral investigations

Objective This meta-analysis aims to investigate the long-term survival rates of dental implants over a 20-year period, providing a practical guide for clinicians while identifying potential areas for future research. Materials and methods Data were sourced fr

Systematic review / meta-analysis 2024
Prevention and public health

Interventions to prevent obesity in children aged 12 to 18 years old.

The Cochrane database of systematic reviews

Background Prevention of obesity in adolescents is an international public health priority. The prevalence of overweight and obesity is over 25% in North and South America, Australia, most of Europe, and the Gulf region. Interventions that aim to prevent obesi

Systematic review / meta-analysis 2023
Diabetes and metabolism

Knowledge, attitude, and practice toward pre-diabetes among the public, patients with pre-diabetes and healthcare professionals: a systematic review.

BMJ open diabetes research & care

The prevalence of pre-diabetes is increasing globally, affecting an estimated 552 million people by 2030. While lifestyle interventions are the first line of defense against progression toward diabetes, information on barriers toward pre-diabetes management an

Systematic review / meta-analysis 2023
Mental health

Neuropsychiatric events associated with montelukast in patients with asthma: a systematic review.

European respiratory review : an official journal of the European Respiratory Society

Background The United States Food and Drug Administration issued a black box warning on the mental health adverse effects of montelukast in 2020. Age-related effects on the risk of developing specific neuropsychiatric events in montelukast users remain largely

Systematic review / meta-analysis 2024
Prevention and public health

Predictive ability of hypotension prediction index and machine learning methods in intraoperative hypotension: a systematic review and meta-analysis.

Journal of translational medicine

Introduction Intraoperative Hypotension (IOH) poses a substantial risk during surgical procedures. The integration of Artificial Intelligence (AI) in predicting IOH holds promise for enhancing detection capabilities, providing an opportunity to improve patient

Systematic review / meta-analysis 2024
Heart and blood vessels

Psychological interventions for depression and anxiety in patients with coronary heart disease, heart failure or atrial fibrillation.

The Cochrane database of systematic reviews

Background Depression and anxiety occur frequently (with reported prevalence rates of around 40%) in individuals with coronary heart disease (CHD), heart failure (HF) or atrial fibrillation (AF) and are associated with a poor prognosis, such as decreased healt

Systematic review / meta-analysis 2023
Infections and immunity

Resilience perspective on healthcare professionals' adaptations to changes and challenges resulting from the COVID-19 pandemic: a meta-synthesis.

BMJ open

Objective To identify, review and synthesise qualitative literature on healthcare professionals' adaptations to changes and challenges resulting from the COVID-19 pandemic. Design Systematic review with meta-synthesis. Data sources Academic Search Elite, CINAH

Systematic review / meta-analysis 2024
Children's health

Systemic juvenile idiopathic arthritis and adult-onset Still's disease are the same disease: evidence from systematic reviews and meta-analyses informing the 2023 EULAR/PReS recommendations for the diagnosis and management of Still's disease.

Annals of the rheumatic diseases

Objectives To analyse the similarity in clinical manifestations and laboratory findings between systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still's disease (AOSD). Methods Three systematic reviews (SR) were performed. One included cohort stud

Systematic review / meta-analysis 2023
General medicine and research

Systemic pharmacological interventions for Ménière's disease.

The Cochrane database of systematic reviews

Background Ménière's disease is a condition that causes recurrent episodes of vertigo, associated with hearing loss and tinnitus. A number of pharmacological interventions have been used in the management of this condition, including betahistine, diuretics, an

Systematic review / meta-analysis 2023
Diabetes and metabolism

The association between body mass index, abdominal fatness, and weight change and the risk of adult asthma: a systematic review and meta-analysis of cohort studies.

Scientific reports

Obesity has been associated with increased risk of adult asthma, however, not all studies have found a clear association between overweight and the incidence of asthma, and data on other adiposity measures have been limited. Hence, we aimed to summarize eviden

Systematic review / meta-analysis 2024
Diabetes and metabolism

The effects of combined exercise training on glucose metabolism and inflammatory markers in sedentary adults: a systematic review and meta-analysis.

Scientific reports

This systematic review and meta-analysis aimed to determine the magnitude of the effect of combined exercise training on glucose metabolism markers, adipokines, and inflammatory cytokines in non-diabetic sedentary adults. PubMed, Web of Science, Scopus, Cochra

Systematic review / meta-analysis 2023
Lungs and breathing

Unsupervised home spirometry <i>versus</i> supervised clinic spirometry for respiratory disease: a systematic methodology review and meta-analysis.

European respiratory review : an official journal of the European Respiratory Society

Background The number of patients completing unsupervised home spirometry has recently increased due to more widely available portable technology and the COVID-19 pandemic, despite a lack of solid evidence to support it. This systematic methodology review and

Systematic review / meta-analysis 2023
Heart and blood vessels

Usability of Telehealth Systems for Noncommunicable Diseases in Primary Care From the COVID-19 Pandemic Onward: Systematic Review.

Journal of medical Internet research

Background During the COVID-19 pandemic, telehealth was expanded without the opportunity to extensively evaluate the adopted technology's usability. Objective We aimed to synthesize evidence on health professionals' perceptions regarding the usability of teleh