Povezanost između ponašanja kod pušenja i opstruktivne apneje u snu: Sistematski pregled i meta-analiza.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Sažetak istraživanja
Uvod Za sistematski pregled povezanosti pušačkog ponašanja i opstruktivne apneje u snu (OSA).
Ciljevi i metode PubMed, Medline, Cochrane Library, EMBASE i Scopus baze podataka korišćene su za sprovođenje ovog pregleda. Dva istraživača su nezavisno pregledala literaturu, izvršila ocjenu kvaliteta i ekstrakciju podataka prema kriterijima uključivanja i isključenja. RevMan 5.3 je korišten za analizu indeksa apnea hipopneje indeksa (AHI), minimalne zasićenosti oksihemoglobina (SaO2), rezultata Epworthove skale pospanosti (ESS) i indeksa desaturacije kisikom (DOI) i analize pristranosti objavljivanja kako bi se procijenio učinak pušenja na pacijente sa OSA. Nadalje, izvršili smo podgrupe težine OSA, različite zemlje porijekla uzorka (zapadne zemlje ili istočne zemlje) i godine pakovanja (PY rezultati U ovu analizu uključeno je trinaest studija koje su bile u skladu sa kriterijumima uključivanja i kriterijumima isključenja. Ukupno 3654 pušača i 9796 nepušača su značajno učestvovale u metaboličnim studijama sa višim nivoima HI13. u grupi pušača u usporedbi s nepušačima, ESS rezultati su također bili značajno viši u grupi pušača u usporedbi s nepušačima, minimalni nivoi SaO2 su bili očito niži u grupi pušača u odnosu na nepušače, međutim, nivoi DOI nisu se značajno razlikovali između dvije grupe. Teški pušači s više od 20 PY bili su pod većim rizikom od OSA, štoviše, pacijenti s teškom OSA su pokazali značajnu povezanost s pušenjem u usporedbi s pacijentima s blagom ili umjerenom OSA. Teški pušači s više od 20 PY u anamnezi bili su pod većim rizikom od OSA, štoviše, pacijenti s teškom OSA su pokazali značajnu povezanost s pušenjem u usporedbi s pacijentima s blagom ili umjerenom OSA-om, preporuča se više prospektivnih dugoročnih studija o efektu prestanka pušenja na OSA.
Prikaži originalni naslov i sažetak na engleskom
Association Between Smoking Behavior and Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis.
Introduction To systematically review the association between smoking behavior and obstructive sleep apnea (OSA). Aims and methods PubMed, Medline, the Cochrane Library, EMBASE, and Scopus databases were used to conduct this review. The two researchers independently screened the literatures, conducted the quality assessment, and data extraction according to the inclusion and exclusion criteria. The RevMan 5.3 was used to analysis the apnea hypopnea index (AHI) index, min saturation of oxyhemoglobin (SaO2), Epworth Sleepiness Scale (ESS) score, and oxygen desaturation index (DOI) and publication bias analysis to assess the effect of smoking on OSA patients. Furthermore, we performed subgroup of the severity of OSA, different countries of sample origin (western countries or eastern countries), and pack-years (PYs
Results Thirteen studies were included in this analysis that conformed to inclusion criteria and exclusion criteria. Totally 3654 smokers and 9796 non-smokers have participated. The meta-analysis of 13 studies demonstrated that AHI levels were significantly higher in smoker group compared with non-smoker, ESS scores were also significantly higher in smoker group compared with non-smoker, min SaO2 levels were obviously lower in smoker group compared with non-smoker, however, DOI levels hadn't significantly different between two groups. The subgroup analysis showed that there was an association between severe OSA, eastern countries, pack-years, and smoking.
Conclusions Smoking behavior is a significant association with OSA. Heavy smokers with histories of more than 20 PYs were at a higher risk of OSA. Moreover, patient with severe OSA exhibited a significantly association with smoking compared with patients with mild or moderate OSA. Implications The relationship between smoking and OSA was controversial, especially, whether smoking increase or aggravate the risk of OSA. In our review and meta-analysis, we demonstrated that smoking behavior is a significant association with OSA. Heavy smokers with histories of more than 20 PYs were at a higher risk of OSA. Moreover, patient with severe OSA exhibited a significant association with smoking compared with patients with mild or moderate OSA. More prospective long-term follow-up studies about effect of quit smoking on OSA are recommended to establish the further relationship.
Izvorni podaci
- DOI
- 10.1093/ntr/ntac126
- PMID
- 35922388
- PMCID
- PMC9910143
- Provjereno
- 2026-07-26
Naslov i sažetak prevedeni su automatski i prijevod može sadržavati netačnosti ili neprecizne stručne izraze. Za sve detalje, citiranje i medicinsko tumačenje pregledajte originalnu englesku verziju članka. Ne donosite zdravstvene odluke samo na osnovu ovog prijevoda.
Pregledaj originalni članak na engleskom